Volume No. 7 Issue No.: 2A Page No.: 1032-1036 Oct. - Dec. 2012

 

STUDIES ON EFFECT OF ROOT EXTRACTS OF Withania somnifera ON SOME CLINICALLY ISOLATED BACTERIAL PATHOGENS

 

Pujari S. A.* and Gandhi M. B.

Department of Microbiology,Yashwantrao Chavan College of Science,Karad, Satara, Maharashtra (INDIA)

 

Received on : September 10, 2012

 

ABSTRACT

 

Withania somnifera commonly called as Ashwagandha is the major Indian medicinal plant used in Ayurveda. The present study evaluates the antibacterial activity of ethanolic, chloroform and aqueous extracts of Withania somnifera roots against three clinically isolated bacterial pathogens viz. Staphylococcus aureus, Salmonella typhi and Shigella dysenteriae causing infections in human beings. The study revealed that the crude ethanol root extract was more effective in inhibiting pathogens as compared to chloroform and aqueous root extracts as determined by agar diffusion method using respective solvents as negative controls. The results obtained in the study indicates that the ethanol extract of Withania somnifera roots might be exploited as natural drug for the treatment of several infectious diseases caused by these pathogens.

 

Keywords : Antibacterial activity, Withania somnifera, Agar diffusion, Pathogens, Clinically isolated bacterial

 

 

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