Volume No. 7 Issue No.: 2A Page No.: 838-843 Oct. - Dec. 2012

 

HIGH CONTENT OF AFLATOXIN IN THE INDIGENOUS FOODS AS POSSIBLE RISK FACTOR FOR LIVER CANCER : AN EXPERIENCE FROM ASSAM, INDIA

 

Medhi Subhash, Deka Manab1, Sarma Manash Pratim *, Bhattacharjee Minakshi, Ghaznavi Idris Md. and Ahmed Giasuddin2

1. Department of Biological Sciences, Gauhati University, Guwahati, Assam (INDIA)
2. Department of Biotechnology, Gauhati University, Guwahati, Assam (INDIA)

 

Received on : September 10, 2012

 

ABSTRACT

 

To analyze total aflatoxin content in various indigenous food items from commercial market of Assam, India as well as AFB-N7 guanine levels among healthy population. Aflatoxin is naturally occurring mycotoxins produced mainly by Aspergillus flavus and A. parasiticus in which aflatoxin B1 is the most potent toxin. Seasonal variations and climatic conditions of Assam have been found to be favourable for aflatoxin producing fungi. A total of thirty food samples consumed by indigenous people of Assam have been analyzed for aflatoxin content during the rainy season. Aflatoxin concentration was estimated in urine by commercially available ELISA kit. The highest aflatoxin were detected in Colocasia esculenta (L.) >6500 ppb followed by Houttuynia cordata (Thumb) > 5600 ppb and Oxalis corniculata (L.). In urine 8% of the healthy population has been detected for AFB-N7 guanine levels above the permissible limit of 30 ppb as prescribed for India. High content of aflatoxin in some of the commonly used food item and urine sample of Assam need further evaluation as possible risk factor in liver disease patients. Some of the commonly consumed and indigenous food stuff from Assam contains aflatoxin in high concentration and may be a possible reason for increased cancer incidence from this part of the country and needs further investigation.

 

Keywords : Indigenous food, Aflatoxin, Liver, Cancer, Toxicity, Urine, Mycotoxin, ELISA

 

 

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