Volume No. 7 Issue No.: 1A Page No.: 584-589 July-September 2012

 

EXPOSURES OF ENVIRONMENT FOR RISK OF ORAL CANCER

 

Sharma Nishant *1,2, Srivastav B.R.1 and Shrivatav Archna2

1. Cancer Hospital and Research Institute, Gwalior (India) 2. College of Life Sciences, Gwalior (India)

 

Received on : May 15,2012

 

ABSTRACT

 

Exposure to a wide variety of natural and man-made substances in the environment plays a key role for risk of oral cancer. Stress, physical and mental abuse, nutrition and diet, exposure to toxins, pathogens, radiation and chemical as environmental factors and determinants of growth and body composition can contribute to the risk of some human cancers such as oral cancer. This article explains which factors of environmental plays a role on carcinogenesis, especially focusing on oral cancers. These factor reduces, repair of DNA damage and control of cell signaling and cell cycle in the effect of environment exposure. Tobacco, alcohol consumption is the most important identified cause of oral cancer followed by exposure to toxins, nutrition and diet, physical activity, infections due to viruses and radiation.

 

Keywords : Oral cancer, Environmental factors, DNA, Cell signalling, Nutrition

 

 

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