Volume No. 6 Issue No.: 4 Page No.: 1019-1023 April-June 2012

 

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY STUDIES OF 2-(2-(5-BENZOYL-1-H-1,2,3-BENZOTRIAZOLE-1-YL)2-OXOETHYLAMINO) BENZOIC ACID AND THEIR TRANSITION METAL CHELATES

 

P.S. Desai* and D.V. Parekh

Department of Chemistry, Arts, Science and Commerce College, Kamrej Char Rasta, Surat (INDIA)

 

Received on : March 05,2012

 

ABSTRACT

 

1-(5-benzoyl-1H-1,2,3-benzotriazole-1-yl)2-chloroethanone was condensed with 2-amino benzoic acid (Anthranilic acid). The resulting 2-(2-(5-benzoyl-1H-1,2,3-benzotriazole-1-yl)2-oxoethylamino) benzoic acid was characterized by elemental analysis and spectral studies. The transition metal chelates of the same were prepared with Cu2+, Ni2+ , Co2+, Mn2+ and Zn2+ and characterized by IR spectral studies and magnetic properties. The antimicrobial activity of ligand and its metal chelates were screened against various gram-positive (+) and gram-negative (%) organism. The results show that all these samples are more or less active agents against various organisms.

 

Keywords : 5-benzoyl-1H-benzotriazole, Anthranilic acid, Metal chelates, spectral studies, Magnetic moment, Antibacterial and antifungal activity

 

 

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