Volume No. 6 Issue No.: 1 Page No.: 51-56 July-Sept 2011

 

SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF SOME TRANSITION METAL COMPLEXES WITH NOVEL BIDENTATE AROMATIC SCHIFF BASE

 

Anish Chandra Pandey1, Richa Kothari* and Brajraj Sharma2

1. Department of PG Studies and Research in Chemistry, SLP Government P.G. College (Jiwaji University), Gwalior (INDIA)
2. Department of Engneering Chemistry, Institute of Technology and Management, Gwalior (INDIA)

 

Received on : April 27, 2011

 

ABSTRACT

 

Metal complexes of Co (II), Ni (II), Cu (II), Zn (II), Cd (II) and Hg (II) with a new Schiff base derived from 2-pyridyl carboxylaldehyde and O-Phenylenediamine in methanol are reported. The complexes have been characterized using chemical analysis, spectroscopic methods (IR, UV-VIS, H1NMR), conductometric and magnetic data. According to these data, we propose an octahedral geometry for metal (II) complexes. The invitro antibacterial activities of the investigated complexes were evaluated against few microorganisms by well diffusion technique. It was found that the metal complexes have higher activity that the standard drugs. Antibacterial activity of the ligand and its complexes were studied against to gram positive bacteria; Staphylococcus aureus and Bacillus subtilis and gram negative bacteria Salmonella typhi and E. coli.

 

Keywords : Schiff base, Metal complexes, Antibacterial activity, Micro-analytical techniques, Spectroscopic methods, Octahedral geometry

 

 

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