Volume No. 5 Issue No.: 3 Page No.: 652-655 January-March 2011




Meena Varma, Deependra Kumar Sharma*, Sangeeta Paaneri1, Avanish Mishra, A. R. S. Sinha

1. Department of Biochemistry, M.G.M. Medical College and Associated Hospital, Indore (INDIA)
2. Department of Biochemistry, Sri Aurobindo Institute of Medical Sciences, Indore (INDIA)


Received on : July 24, 2010




There has been world wide acceptance of herbal medicines for health care, it has drawn attention of researchers towards exploration of bioactivities of medicinal plants used in conjunction with other drugs and as an alternative medicine. A study was done to evaluate the hypoglycemic and hypolipidemic effect of garlic pods administration. The criteria of inclusion of the study group patients was FBS > 110 mg/dl of glucose, > 290 mg/dl of cholesterol, > 210 mg/dl of triglyceride < 30 mg/dl HDL and > 180 mg/dl of LDL. All the subjects were examined for fasting serum glucose, MDA and serum lipids (cholesterol, LDL, HDL and TG). Garlic pods (100 mgs/day) were given to the study group for 5 months and samples were collected every month for estimation of all parameters under study. The study has shown that the garlic pods significantly decrease serum glucose, MDA as well as serum Lipids (Total Cholesterol, Triglyceride and LDL) in the study group. This effect was seen from the first month of administration of garlic and the peek effect was in 3 months which remained same up to 5 months. The results show that there was a significant increase in glucose, cholesterol, HDL and triglycerides in obese patients with recently diagnosed Diabetes mellitus type II. But after treatment with garlic pods there was significant lowering of serum glucose, MDA, cholesterol and triglycerides and these values were close to normal. A single increase in HDL level was also seen. This indicates that the garlic has antidiabetic, antilipidic and antioxidant property


Keywords : Garlic, Antidiabetic, Antilipidic, Antioxidant, Total cholesterol