Volume No. 3 Issue No.: 3 Page No.: 873-878 Jan-Mar 2009




Ratna Roy

Department of Chemistry, Government M.L.B. Girls


Received on : November 13, 2008




Water found in nature is not pure in the chemical sense, but natural water are not regarded as polluted. Impurities in traces are universal for water. We get concerned only when its physical, chemical or biological characteristic deteriorate and becomes harmful to man. The causes of chemical pollution are of numerous types one of which is toxic metal ion. Under present investigation the cause, analysis, and impact of Arsenic pollution on human life is being observed.
In traces Arsenic is found everywhere and it enters the environment from natural and manmade sources. There is continuous cycling of Arsenic through the air, oceans and land all the time. Arsenic enters the living world in the body of plants and animals from the soil and water, and is released through combustion, decomposition and volatilisation. It is used in alloys, pesticides, wood preservatives and some medical preparations. It was formerly used in paint pigments but this use discontinued, when it was found that under dump conditions, moulds converted the arsenic to the highly toxic gases arsine, and trimethyl arsine. It is also present in many sulphide ores of metals and is therefore emitted from metal smelters as an atmospheric pollutant Coal also contain significant amount of Arsenic and its combustion accounts for 20% of atmospheric emission. Coal ashes are also a significant source of Arsenic which can be leached into water or the soil.
The toxicological importance of Arsenic is partly due to its chemical similarity with Phosphorous which means that Arsenic can disrupt metabolic pathways involving Phosphorous Both acute and chronic toxicity are recognised. Arsenic is a cumulative poison, causing, vomiting and abdominal pains prior to death. It may also cause dermatitis and bronchitis and may be carcinogenic to tissues of the mouth, oesophagus, larynx and bladder. At the cell level it can uncouple oxidative phosphorylation and compete with Phosphorous in metabollic reactions. The sensitivity of organisms to the metal toxicity varies widely with species of plants and animals and genotypes within species. Many factors can modify the response to the toxic dose of metals. Hutton has given 200 ?g/litre of As in drinking water is the threshold value for 5% prevalence of skin cancer for the life time exposure (70 yrs.) Arsenic is concentrated by organisms exposed to it and accumulates along food chains. Hence no need to say that Arsenic is highly dangerous substance for human health.


Keywords : Dermatitis, Genotype, Combustion Arsine, Phosphorylation, Carcinogenic.?