Volume No. 1 Issue No.: 1 Page No.: 54-58 July-September 2006

 

IN VITRO STUDY OF EFFECT OF HONEY ON ENVIRONMENTAL POLLUTANTS PRODUCED LIPID PEROXIDASE ACTIVITY IN GOAT LIVER

 

A. Jain* and S.D. Belsare

Department of Biosciences, Barkatullah University, Bhopal-462016 (India)

 

Received on : April 01, 2006

 

ABSTRACT

 

The LPO (increased production of environmental pollutants) activity in goat liver was studied by adding 10, 20 & 30 ppm concentration of sodium salicylate in liver slices (0.5 x 0.5 x 0.5 mm), which were kept in the Kreb ringer’S buffer solution pH (7.4). The effect of honey at various concentrations (5 x103, 10 x103, 15 x103, 20 x103, 25 x103 ppm) was seen after salicylate treatment in vitro. The administration of salicylate resulted increase in LPO level of goat liver, because of increased production of free radicals (environmental pollutants), whereas when honey was added 1 hour after salicylate administration it was restored to normal level within 1 hour. These observations suggest that honey lowers down LPO level of liver slices by scavenging lipid radicals, especially free fatty acids (FFA) produced by the drug salicylate, so it decreases environmental pollutants in our environment thus lower down environmental pollution, this effect is due to antioxidant property of honey is discussed in this report.

 

Keywords : Goat Liver, Environmental Pollutants, Lipid Peroxidation, Sodium Salicylate, Honey

 

 

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