Volume No. 8 Issue No.: 3 Page No.: 437-442 Jan-Mar 2014

 

SYNTHESIS, CHARACTERIZATION AND ANTIMICR-OBIAL ACTIVITY STUDIES OF (E)-Ní-(2-(2-(SUBSTI-TUTED BENZALDEHYDE) HYDRAZINYL) QUIN-AZOLINE-4-YL) ISONICOTINOHYDRAZIDE

 

Naik P.J. and Desai P.S.*

Department of Chemistry, Arts, Science and Commerce College, Surat (INDIA)

 

Received on : October 01, 2013

 

ABSTRACT

 

The compounds have been synthesized by refluxing the N'-(2-hydrazinoquinazolin-4-yl)isonicotinohydrazide and different substituted aldehyde in presence of acid catalyst to yield (E)-N'-(2-(2-(substitutedbenzalidene) hydrazinyl) quinazolin-4-yl) isonicotino hydrazide using conventional methods and studied their biological activities.

 

Keywords : 2, 4-dichloroquinazoline, Isoniazid, IR/NMR spectroscopy, Antibacterial, Antifungal activities

 

 

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