Volume No. 9 Issue No.: 4 Page No.: 1168-1171 April-June 2015

 

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NEW SCHIFF BASES OF 1,3- BIS(P-CHLOROANILIDO) PROPANE-1,3-DIONE

 

Alka Pradhan* and Anil Kumar Koshal

Department of Chemistry, Govt. Motilal Vigyan Mahavidhalaya, Bhopal, M.P. (INDIA)

 

Received on : December 10, 2014

 

ABSTRACT

 

The present investigation includes the synthesis and characterization of new Schiff bases and their biological activities. Thirteen new different substituted Schiff bases were synthesized by condensation of synthesized 1,3-bis(p-Chlorodianilido)propane-1,3-dione with different aromatic substituted amine. The structure of Schiff bases have been confirmed by their IR spectra and elemental analysis. All the new compound synthesized have been evaluated for their inhibitory action against both gram positive and gram negative bacteria.

 

Keywords : Schiff bases, Biological evaluation, Elemental analysis, Electronic spectra

 

 

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