Volume No. 8 Issue No.: 1 Page No.: 27-32 Jul-Sept. 2013

 

MICROSOME TECHNOLOGY AS A POTENTIAL BIOREMEDIATION OPTION FOR HEALTH AND ENVIRONMENTAL PROTECTION

 

Singh Ved Pal *, Kumar Rajesh, Singh Ishwar and Srivastava Shikha

Applied Microbiology and Biotechnology Laboratory, Department of Botany, University of Delhi, Delhi (INDIA)

 

Received on : April 05, 2013

 

ABSTRACT

 

With the increase in the global population, there has been tremendous increase in the diverse kinds of pollutants/hazardous compounds of anthropogenic origin, generated by agricultural/industrial sectors, which pose potential threat to both health and environment. Most foods, feeds and other agricultural produce get contaminated with fungi that produce mycotoxins; and aflatoxins produced by Aspergillus flavus constitute the major ones and most wide studied toxins, which are mutagenic, carcinogenic as well as teratogenic in nature. In the present investigation, an attempt has been made to degrade/detoxify these fungal toxins, using the microsomes of microbial origin. Interestingly enough, the microsomes isolated from the toxigenic strain of A. flavus were able to degrade/detoxify aflatoxins produced by that very fungus itself. Not only that, the microsomes from nonpathogenic and nontoxigenic strains of microorganisms, including bacteria and fungi could degrade aflatoxins quite efficiently. Thus, microsome-based strategy or Microsome Technology can serve as a viable option/potential tool for bioremediation of hazardous compounds, so as to safeguard/protect both human and animal health as well as the environment. In this paper, we have highlighted the significance of Microsome Technology for the benefit of mankind, in terms of its applicability for bioremediation of xenobiotics of health and environmental concern.

 

Keywords : Bioremediation, Environmental, Protection, Microsome Technology, A. flavas

 

 

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